Exchanges At The Frontier

Episodes

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2013020920130210 (WS)

AC Grayling and a public audience question the world’s leading scientists about the imp...

AC Grayling and a public audience question the world’s leading scientists about the impact of their work: Frances Ashcroft.

Is Pain an Emotion?20160213

Professor Irene Tracey is known as the Queen of Pain. Her work demonstrates how simple pain can develop into chronic pain, how our emotions can override the effect of pain killers and what anaesthesia can tell us about consciousness.

Image credit: Dental Instruments, Wellcome Library, London

Is Pain an Emotion?2016021320160214 (WS)

Irene Tracey known as the Queen of Pain shows how the brain can be easily tricked

Is Pain an Emotion?20160213

J.n. Goswami20131102

Justin Rowlatt meets Professor Jitendra Nath Goswami in Ahmedabad, to discuss India's Mars Orbiter Mission.

Jeremy Farrar - Epidemiologist2013020220130203 (WS)

What if anything can be done to allay the risks of global epidemics?

Philosopher AC Grayling and a public audience question the world's leading scientists about the impact and importance of their work for this year's Exchanges at the Frontier.

In the second programme, Clinician and Director of Oxford University’s Vietnam Infectious Disease Research Unit, Jeremy Farrar joins Grayling at the Wellcome Collection in London. Farrar will discuss the global risks of Sars and influenza and what, if anything can be done to allay the risks of global epidemics.

Jeremy Farrar knows as much about the influenza virus as anyone on the planet. He is a doctor, an epidemiologist, the holder of the Ho Chi Minh Medal from the Government of Vietnam and the British OBE; he is the Director of the Clinical Research Unit of Infectious Disease Hospital in Ho Chi Minh City, Vietnam and the Director of the South East Asia Infectious Disease Clinical Research Network.

(Image: Swine flu virus, Credit: Novartis)

Jitendra Goswami2013110220131105 (WS)

What is the motivation behind India's mission to Mars?

Jitendra Goswami20131102

Whilst NASA is cutting its space budget, India has launched a mission to Mars. What is the motivation behind India's Mars Orbiter Mission, the 300 million kilometre interplanetary expedition? Jitendra Goswami is the lead scientist of India’s first mission to Mars. Before the launch, he spoke to Justin Rowlatt and an audience in Ahmedabad, India about space science and earthly economics.

Picture: JN Goswani, Credit: Dibyangshu Sarkar/AFP/Getty Images

Jitendra Goswami20131102

What is the motivation behind India's mission to Mars?

Robert Langer - Biochemical Engineer2013012620130127 (WS)

What treatments are in the pipeline from the realm of medical tissue engineering?

Philosopher AC Grayling and a public audience question the world's leading scientists about the impact and importance of their work for this year's Exchanges at the Frontier.

Robert Langer heads an extraordinary biochemical laboratory. He and his team have developed treatments which are in use in every major hospital in the world including locally delivered chemotherapy, artificially-generated human tissue, tumour growth restrictors and gel that fixes damaged vocal chords.

Langer is a founding father of tissue engineering and controlled drug release and is unusual as an academic in that his discoveries have led to him hold over 800 patents, found 25 companies and license his technology to 250 more.

Anthony Grayling and an audience drawn from the world of biochemistry put questions to Langer and asked him about his unique approach to the challenges that illness poses and the life-saving devices he has in the pipeline.

Robert Langer is David H Koch Institute Professor at MIT, USA. Last year Langer won the Joseph Priestly prize for chemistry, and in 2002 he won the Charles Draper Award – considered the Nobel Prize for engineering, both pursuits which are traditionally a long way from medicine where he has made his indelible mark.

(Image: AC Grayling (left) and Robert Langer (right), Credit: Justin Knight)

Supermassive Black Holes and the Evolution of Galaxies20160305

Black holes are intriguing and mysterious objects in space from which no light can escape. The existence of black holes or dark stars was first hinted at in the 18th Century by John Michell and Pierre-Simon Laplace.

Their theories were abandoned and its only comparatively recently that scientists have been able to study them and appreciate the importance of black holes in the formation of galaxies.

Situated at the peak of the Cerro Pachon Mountain in the Chilean Andes is the Gemini South Observatory and from there astrophysicist professor Thaisa Storchi Bergmann investigates super-massive black holes and their host galaxies, the building blocks of the Universe.

Based at Brazil’s Federal University of Rio Grande do Sul professor Storchi Bergmann has dedicated her career to the study of super-massive black holes and their role in the evolution of galaxies. As she tells Tom Service her eureka moment came when she saw the signs of a star falling into a black hole in a galaxy 20 million light years away, an event predicted to happen only once every 10,000 years.

(Photo: Evidence of Black Holes, Credit: Nasa)

Supermassive Black Holes and the Evolution of Galaxies2016030520160306 (WS)

A once in 10,000 year event gave astrophysicist Thaisa Storchi Bergman her eureka moment

Supermassive Black Holes and the Evolution of Galaxies20160305

The Search for Hunger Genes2016022020160221 (WS)

Professor Sadaf Farooqi looks at why some people put on weight and others don’t

The Search for Hunger Genes20160220

Most people tend to overeat given a generous supply of appetising food, but some don’t put on weight while others do. Sadaaf Farooqi, professor of Metabolism and Medicine at Cambridge investigates the genetics of obesity, the brain’s response to food and how hormones influence metabolism and weight. Many myths surrounding weight gain such as a slow metabolism or, it’s my genes doctor, turn out to be true.

So should we be more compassionate to people who struggle with their weight?

In front of an audience of London Sixth formers at the Wellcome Collection she tells Claudia Hammond how only eating an extra slice of cucumber per day could cause an increase in weight.

(Photo: Statue to illustrate obesity - I Cannot Help the Way I Feel by John Isaacs. Credit: Wellcome Collection)

The Search for Hunger Genes20160220

The Search for Neanderthal Genes20160312

What does the DNA of our closest ancestors tell us about ourselves? Professor Svante Paabo is director of the Max Planck Institute for Evolutionary Anthropology and he tells Robin Ince about being one of the first people in the world to start looking at ancient DNA. From his early work with Egyptian mummies to his breath taking achievement of sequencing the genome of our nearest ancient relatives - the Neanderthals - he has changed how we think about ourselves. His current work is to understand why humans survived and Neanderthals became extinct. Professor Paabo and his team have found a comparatively small number of changes in the genes between us and Neanderthals including changes in the brain. Could these differences explain what makes us human.

(Photo: Skull of neanderthal man)

The Search for Neanderthal Genes2016031220160313 (WS)

How much of a Neanderthal are you? Svante Paabo reveals the secrets of our genes

The Search for Neanderthal Genes20160312

01Exchanges At The Frontier2014020820140209 (WS)

AC Grayling speaks to Bonnie Bassler, the world specialist in how bacteria communicate...

AC Grayling speaks to Bonnie Bassler, the world specialist in how bacteria communicate within the human body.

01Exchanges At The Frontier 2011, - Sir Paul Nurse20111126

Sir Paul Nurse is a Nobel Prize-winning cell biologist and the new President of The Royal Society, the oldest science establishment in the world.

He is a trail-blazing geneticist as well as director of the new Francis Crick Institute, set to be the world's biggest biomedical research centre when it opens in London in 2015.

Join him in conversation about the cell cycle, trying to cure cancer and his thoughts for the future of science.

AC Grayling in conversation with Sir Paul Nurse, a Nobel Prize-winning cell biologist

01Exchanges At The Frontier 2011, - Sir Paul Nurse20111127

AC Grayling in conversation with Sir Paul Nurse, a Nobel Prize-winning cell biologist

02Exchanges At The Frontier2014021520140216 (WS)

AC Grayling speaks to Henry Markram, who is building a super computer which will virtua...

AC Grayling speaks to Henry Markram, who is building a super computer which will virtually replicate the human brain.

02Exchanges At The Frontier 2011, - Vilayanur Ramachandran20111203

Vilayanur Ramachandran has been called the Marco Polo of neuroscience.

How do you cure excruciating pain in a limb that no longer exits?

Professor Ramachandran's extraordinary low tech solutions have completely alleviated phantom limb pain for many people and present possibilities for the treatment of conditions like autism.

He is the Director of the Center for Brain and Cognition at the University of California, San Diego.

Join him in conversation as he demonstrates some of the simple experiments which reveal hidden truths about all of our brains.

(Image: Human brain held inside a room in a brain bank.

Credit: Science Photo Library)

AC Grayling in conversation with Vilayanur Ramachandran, the 'Marco Polo' of neuroscience

02Exchanges At The Frontier 2011, - Vilayanur Ramachandran20111204

AC Grayling in conversation with Vilayanur Ramachandran, the 'Marco Polo' of neuroscience

03Exchanges At The Frontier2014022220140223 (WS)

Matthew Sweet speaks to Iain Couzin, a specialist in collective animal behaviour.

Matthew Sweet speaks to Iain Couzin, a specialist in collective animal behaviour, about dealing with locusts destroying crops.

03Exchanges At The Frontier 2011, - Valerie Mizrahi20111210

Valerie Mizrahi is the Director of the Institute of Infectious Disease and Molecular Medicine at the University of Cape Town, where she has done ground-breaking work on tuberculosis.

It was once thought to be almost eradicated but now it is estimated that a third of the world's population is infected with TB.

It is the biggest killer amongst HIV positive people, claiming nearly two million lives every year.

With its links to Aids it is a controversial subject in South Africa, where Professor Mizrahi pioneers work on HIV and TB.

Join her in conversation AC Grayling, about her zeal for medical research and her determination to bring life saving innovations to the developing world.

(Image: Mycobacterium tuberculosis bacteria.

Credit: Science Photo Library)

AC Grayling in conversation with Valerie Mizrahi, who has done ground-breaking work on TB.

03Exchanges At The Frontier 2011, - Valerie Mizrahi20111211

AC Grayling in conversation with Valerie Mizrahi, who has done ground-breaking work on TB.

04Exchanges At The Frontier 201120111217

Some of the world's leading scientists are quizzed on the impact of their work by the philosopher Anthony Grayling.

Some of the world's leading scientists are quizzed on the impact of their work by the p.

04Exchanges At The Frontier 2011, - Gebisa Ejeta20111218

Gebisa Ejeta is an Ethiopian born award-winning plant scientist working on drought-resistant crops in Africa.

He has experienced hunger first hand during his childhood in Ethiopia and is now an advisor to President Barrack Obama as well as a being World Food Prize Laureate and Distinguished Professor at Purdue University, USA.

Join him in conversation about addressing the food crisis in Horn of Africa and abolishing famine world wide.

(Image: A malnourished child in Somalia.

Credit: Reuters)

AC Grayling in conversation with Gebisa Ejeta, can he help abolish famine world wide?

04 LASTExchanges At The Frontier2014030120140302 (WS)

Psychologist Kay Redfield Jamison on the disastrous highs and lows of bipolar disorder

Kay Redfield Jamison is a clinical psychologist with a rare insight. She is a world leader in the study of bipolar (manic-depressive) illness, a condition that she herself has had since adolescence. As a highly regarded clinician with direct experience of the illness she treats, she has a special perspective on the debilitating nature of this psychiatric disorder and its seductive but disastrous highs, depressions and disordered thinking. She tells A.C.Grayling and an audience at Wellcome Collection in London about mania, creativity and the best medicine for an extraordinary condition.

05 LASTExchanges At The Frontier 2011, - Steven Pinker20111224

Steven Pinker is one of the world's leading authorities on language and the mind.

He is also Johnstone Family Professor of Psychology at Harvard University and the recipient of several major awards for his teaching, books, and scientific research.

Join him in discussion about language acquisition, the nature of the mind and the effect of evolution on the development of human society.

AC Grayling in conversation with Steven Pinker, a leading authority on language and mind

05 LASTExchanges At The Frontier 2011, - Steven Pinker20111225

Steven Pinker is one of the world's leading authorities on language and the mind.

He is also Johnstone Family Professor of Psychology at Harvard University and the recipient of several major awards for his teaching, books, and scientific research.

Join him in discussion about language acquisition, the nature of the mind and the effect of evolution on the development of human society.

AC Grayling in conversation with Steven Pinker, a leading authority on language and mind